Professor Makrides is an international leader in maternal-infant nutrition and is recognised for her work investigating the health effects of dietary fatty acids, iron and novel dietary ingredients in the perinatal period. Her work has made significant contributions to changes in the composition of infant formulae and on changing international food laws (Codex Alimentarius), which determine the minimum safe composition of infant foods. Her multi-disciplinary research group, with over 30 staff, conducts large scale randomised controlled trials, with a focus on optimising the cognition, growth and immune development of children. Through these trials, her group has directly engaged with over 10,000 families.