Prof Goodall is a world leader in the biology of RNA and cancer progression. He has combined innovation with thoroughness to make discoveries that open new areas in RNA biology for development and exploitation. He has made seminal contributions to the understanding of mechanisms governing gene activity in cancer, through control of mRNA activity, regulation of gene expression by microRNAs, and most recently discovery of regulation of circular RNAs. These discoveries have widespread implications for understanding gene regulation in general, and in particular in immunity and cancer. His publications have received over 5000 citations in the past 5 years alone.