Professor Murphy has had more than 30 years of leadership roles in the Australian Public Health system, with two distinct career phases. His initial contribution was as a clinician researcher, during which he directed a busy renal unit, lead his own research group which, inter alia, identified and characterised novel human plasma complement inhibitors, was President of the Nephrology Society and a renowned educator. More recently, he has been the longest serving and most successful CEO in the Victorian Public Health system, leading a high performing service, whilst undertaking national leadership roles in workforce reform, end of life care and informatics.