Professor Anthony Keech has made sustained important contributions to clinical and basic research to improve Australian and international health through his career, and continues to do so. He is an internationally-renowned cardiologist and clinical triallist with formal expertise in epidemiology, who co-directs the NHMRC Clinical Trials Centre in Sydney, with over 160 personnel. He has helped to lead global trials of most of the major established treatments for the care of acute myocardial infarction and has influenced policy locally and internationally, especially in the areas of MI care, lipid management to reduce cardiovascular risk and the treatment of diabetes.