Professor Christopher Blyth has made substantial contributions to health, informing international immunisation, infection prevention and management policy and practice. Professor Blyth’s research and advocacy has driven changes to immunisation programs in Australia and internationally. As a member of the Australian Technical Advisory Group on Immunisation (ATAGI 2012-2021; co-chair from 2018-2021), he led Australia’s technical experts informing the national COVID-19 vaccination program. Through leadership and mentoring, he has significantly developed infectious disease and public health research capacity in Australia and the region. Professor Blyth’s capacity to communicate and promote health and science to the broader community have been both recognised and awarded.