Professor Byles is recognised both nationally and internationally for her exceptional leadership and outstanding contribution to public health, women’s health and ageing research. Her work includes examining the role of health services, preventive activities and treatments which maintain quality of life over the life course, determining physical, psychological and social factors associated with optimal physical and mental health of men and women, and developing and evaluating health promotion and health care innovations for older people. As a founding investigator and a Director of the Australian Longitudinal Study on Women’s Health, she has provided a powerful evidence base for policy development and evaluation and has contributed greatly to health care research.