Professor Robert M. Graham is internationally regarded for his contributions to our understanding of cardiovascular homeostatic and disease mechanisms via adrenergic receptors and coupled signal transduction pathways; studies that have utilised the tools of molecular and cell biology, biochemistry and biophysics. Nationally he is recognised for establishing a leading cardiovascular research institute, which also provides comprehensive research training and aims to rapidly translate research advances into improved clinical care. As well as directing the Institute, he remains actively engaged in clinical medicine, in undergraduate and postgraduate teaching, in community engagement and in providing leadership in academic health and medical science.