As Professor of Anatomy and Medicine and founding Director of the Monash Institute of Medical Research, Professor de Krester’s research led to 494 refereed publications and 170 Chapters. He served as President of the International Society of Andrology. His team isolated inhibin and follistatin as FSH regulators and showed that activin A, an FSH stimulator is also a key proinflammatory cytokine. Follistatin, by blocking activin actions, has anti-fibrotic and anti-inflammatory therapeutic potential. His research enhanced infertility management and our understanding of the hormonal regulation of reproduction and aspects of inflammation and fibrosis. He initiated community and professional education program called Andrology Australia.