Professor Degli-Esposti is an eminent researcher of international standing and a leader in the field of viral immunology. She has made multiple seminal contributions to understanding the immunological pathways invoked in response to viral infection and the pathophysiology of the resulting disease. Her work has been the subject of highly cited papers in prestigious journals and she is regularly invited to speak at premier international conferences. Insights from her studies are guiding the improved management of chronic viral infections and their complications, including the development of autoimmunity and transplant-related disease. Professor Degli-Esposti also plays a major service and leadership role.