Professor Anne-Louise Ponsonby has extensive experience in the design, conduct, and analysis of population-based studies and trials. She is a co PI of a large birth cohort that generated knowledge, translated into action, that led to an 80% reduction in sudden infant death syndrome incidence in Australia, from 1.9 per 1,000 live births in 1990 to 0.2 live births in 2012. Ponsonby’s recent work combines population epidemiologic approaches with system biology. Ponsonby has an active role in public health translation, most recently in relation to plastic exposure in early life and the human health effects of chemical mixtures.