Dr Begley’s research contributions include discovery of key factors controlling normal and malignant cells. His demonstration that stem cells, normally resident in bone marrow, can be enriched in blood and hasten patient recovery has revolutionized transplantation approaches. At Amgen over 25 of his research programs entered clinical trials. His work has impacted the lives of millions of cancer patients and has been recognized by election as Fellow, Royal Colleges of Pathologists UK (1997) and Australasia (2002); American Society of Clinical Investigation (2002); Association of American Physicians (2008); and inaugural inductee into the Royal Melbourne Hospital’s Research “Hall of Fame” (2014).